Prevalence and antibiotic sensitivity of uropathogens isolated from type-ii diabetic patients having urinary tract infection (UTI): A retrospective study from a rural tertiary care hospital
| Autor: | Ankita Priyadarshini, Janvi Shah, Hemantkumar Patadia, Ajit K. Gangawane |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International journal of health sciences. :2511-2523 |
| ISSN: | 2550-696X 2550-6978 |
| DOI: | 10.53730/ijhs.v6ns6.9798 |
| Popis: | Background: Patients with Diabetes Mellitus are more prone to Urinary tract infection (UTI) than non-diabetic patients. Diabetes Mellitus has certain negative effects on the genital system and increases the incidence of urinary tract infection in diabetic patients. Design: Record based retrospective study. Methods: Records of patients with type-II diabetes having symptoms of UTI were reviewed from August 2021 to January 2022. Result: Out of 210 diabetic patients, the UTI rate was higher in females 59% than male 41%. The most common agents for causing UTI were E.coli followed by Pseudomonas aeruginosa, Klebsiella spp., Candida albicans and Candida non-albicans, Enterococcus, S.aureus and other organisms. About 70.68% Gram-negative isolates were resistant against ampicillin, 75.17% resistant against gentamycin, and 48.16% resistant against amoxicillin-clavulanic acid. Gram-positive isolates were 83.33% resistant against penicillin and 83.33% resistant against ciprofloxacin. However, both gram-negative and gram-positive were susceptible to nitrofurantoin. The overall multidrug resistance was observed in 201 out of 210 (95.71%) bacterial and candiduria isolates, while 3.33% of the isolates were resistant to one only antibiotic. Conclusion: Most common etiological agent is E.coli with high drug resistance to ampicillin and susceptible to nitrofurantoin. Therefore, performing urine culture and regular monitoring of UTI is essential. |
| Databáze: | OpenAIRE |
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