Efficacy of auditory integration therapy (AIT) on plasma syntaxin1A (STX1A) levels and amelioration of behavioral, social, and sensory symptoms in children with autism spectrum disorder (ASD)

Autor: Laila Yousif Al-Ayadhi, Nadra Elyass Elamin, Dost Muhammad Halepoto, Abdulrahman Mohammed Alhowikan
Rok vydání: 2023
Předmět:
Zdroj: International Journal of ADVANCED AND APPLIED SCIENCES. 10:6-11
ISSN: 2313-3724
2313-626X
DOI: 10.21833/ijaas.2023.04.002
Popis: Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder. Previous research reported the beneficial effects of Auditory Integration Training (AIT) on a considerable range of behavior and learning problems. Limited studies examined the association between AIT and biological biomarkers in autistic subjects. Therefore, this study aims to examine the effect of auditory integrative training on the plasma syntaxin1A protein (STX1A) level and also to assess its impact on behavioral, social, and sensory symptoms in autistic children, using a sandwich enzyme-linked immunoassay (ELISA). Total scores of the Childhood Autism Rating Scale (CARS), Social Responsiveness Scale (SRS), and Short Sensory Profile (SSP) were calculated before one month and three months after AIT for all participants. Results show that the plasma level of STX1A was significantly increased immediately, one month, and three months after AIT (P
Databáze: OpenAIRE
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