Impact of vitamin D insufficiency on insulin homeostasis and beta cell function in nondiabetic male HIV-infected patients
| Autor: | Óscar Moreno-Pérez, Joaquín Portilla, Antonio Picó, Sergio Reus, Esperanza Merino, Vicente Boix, Rocío Alfayate, Corina Escoín, Angela Bernabeu, José Sánchez-Payá, Livia Giner, Montserrat Mauri |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
business.industry Health Policy Insulin medicine.medical_treatment medicine.disease vitamin D deficiency Infectious Diseases Endocrinology Insulin resistance Internal medicine Diabetes mellitus medicine Vitamin D and neurology Glucose homeostasis Pharmacology (medical) Beta cell Lipodystrophy business |
| Zdroj: | HIV Medicine. 14:540-548 |
| ISSN: | 1464-2662 |
| DOI: | 10.1111/hiv.12042 |
| Popis: | Objectives Vitamin D is thought to play a role in glucose homeostasis and beta cell function. Our aim was to examine the impact of plasma 25-hydroxyvitamin D [25(OH)D] upon in vivo insulin sensitivity and beta cell function in HIV-infected male patients without diabetes. Methods A cross-sectional study was carried out involving a cohort of HIV-infected patients undergoing regular assessment in a tertiary hospital. Eighty-nine patients [mean (± standard deviation) age 42 ± 8 years] were included in the study: 14 patients were antiretroviral therapy (ART)-naive, while 75 were on ART. Vitamin D insufficiency (VDI) was defined as 25(OH)D |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|