THYROID STATUS IN CHILDREN WITH TYPE 1 DIABETES MELLITUS
| Autor: | Zakhrokhon Ergashbaeva Zakhrokhon Ergashbaeva, Alfira Muratkhan Alfira Muratkhan, Saiyara Nadyrova Saiyara Nadyrova, Sakhipzhamal Sabirova Sakhipzhamal Sabirova, Zhanar Nurgaliyeva Zhanar Nurgaliyeva, Alfiya Zhanzak Alfiya Zhanzak, Araily Manasbaeva Araily Manasbaeva |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Ambiance in Life International Scientific Journal in Medicine of Southern Caucasus. :71-72 |
| ISSN: | 2346-8181 2346-8068 |
| DOI: | 10.36962/0601202171 |
| Popis: | The mutually aggravating effect of comorbid diseases of diabetes mellitus (DM) and autoimmune thyroiditis (AIT) is of scientific interest to researchers. Timely assessment of the thyroid status in children with DM and correction of thyroid pathology (TP) will improve metabolic control in these patients. Аmong 972 children with DM, 478 (49.2%) were assessed for thyroid status. It is noted that every year the determination of thyroid hormone levels in children increased from 7.6% (in 2014) to 92.1% (in 2019). Among 478 examined children, 319 (66.7%) had significantly revealed thyroid dysfunction. In the structure of thyroid pathologies, the frequency of hypothyroidism was 12.5% (in 11.3% - subclinical form), hyperthyroidism - 4%. functional changes in the concentration of thyroid hormones as Euthyroid sick syndrome were observed in 23.8%. The most common type of dysfunction was an isolated increase in free T3 (isolated T3 toxicosis) – in 43.3% of cases. In 2 cases out of 18 (0.6%), a complete picture of AIT was presented, and in the remaining 16 (5.1%), signs of AIT were observed only on ultrasound of the thyroid gland, and were not confirmed by the concentrations of anti-TPO Ab, anti-TG Ab. In 47 (14.7%) children, laboratory data on thyroid hormone levels showed elevated values of TSH, free T3, free T4. Keywords: children, diabetes mellitus, thyroid status, autoimmune thyroiditis |
| Databáze: | OpenAIRE |
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