Combined Tricuspid and Mitral Versus Isolated Mitral Valve Repair for Severe MR and TR
| Autor: | Michael Mehr, Nicole Karam, Maurizio Taramasso, Taoufik Ouarrak, Steffen Schneider, Philipp Lurz, Ralph Stephan von Bardeleben, Neil Fam, Alberto Pozzoli, Edith Lubos, Peter Boekstegers, Wolfgang Schillinger, Björn Plicht, Holger Eggebrecht, Stephan Baldus, Jochen Senges, Francesco Maisano, Jörg Hausleiter, Kim Connelly, Paolo Denti, Davide Schiavi, Marcel Weber, Georg Nickenig, Christian Frerker, Horst Sievert, Laura Vaskelyte, Ulrich Schäfer, Daniel Kalbacher, Florian Deuschl, Karl-Heinz Kuck, Hannes Allessandrini, Christian Besler, Karl-Philipp Rommel, Tobias Ruf, Mathias Orban, Thomas Stocker, Simon Deseive, Daniel Braun, Michael Näbauer, Steffen Massberg, Raffi Bekeredjian, Christine S. Meyer-Zuern, Giovanni Pedrazzini, Luigi Biasco |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Mitral valve repair
medicine.medical_specialty Mitral regurgitation Tricuspid valve business.industry medicine.medical_treatment 030204 cardiovascular system & hematology medicine.disease Pulmonary hypertension Cardiac surgery 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Internal medicine Mitral valve Heart failure medicine Cardiology 030212 general & internal medicine Cardiology and Cardiovascular Medicine business Survival rate |
| Zdroj: | JACC: Cardiovascular Interventions. 13:543-550 |
| ISSN: | 1936-8798 |
| DOI: | 10.1016/j.jcin.2019.10.023 |
| Popis: | Objectives The aim of this study was to retrospectively compare the characteristics, procedural courses, and outcomes of patients presenting with concomitant mitral regurgitation (MR) and tricuspid regurgitation (TR) in the TriValve (Transcatheter Tricuspid Valve Therapies) and TRAMI (Transcatheter Mitral Valve Interventions) registries. Background Transcatheter mitral edge-to-edge valve repair (TMVR) has been shown to be successful in patients with severe MR. Lately, edge-to-edge repair has also emerged as a possible treatment for severe TR in patients at high risk for cardiac surgery. In patients with both severe MR and TR, the yield of concomitant transcatheter mitral and tricuspid valve repair (TMTVR) for patients at high surgical risk is unknown. Methods The characteristics, procedural data, and 1-year outcomes of all patients in the international multicenter TriValve registry and the German multicenter TRAMI registry, who presented with both severe MR and TR, were retrospectively compared. Patients in TRAMI (n = 106) underwent isolated TMVR, while those in TriValve (n = 122) additionally underwent concurrent TMTVR in compassionate and/or off-label use. Results All 228 patients (mean age 77 ± 8 years, 44.3% women) presented with significant dyspnea at baseline (New York Heart Association functional class III or IV in 93.9%), without any differences in the rates of pulmonary hypertension and chronic pulmonary disease. The proportion of patients with left ventricular ejection fraction Conclusions Concurrent TMTVR was associated with a higher 1-year survival rate compared with isolated TMVR in patients with both MR and TR. Further randomized trials are needed to confirm these results. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|