SIMULTANEOUS ESTIMATION AND VALIDATION OF PARACETAMOL, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE HYDROCHLORIDE, CAFFEINE AND ITS STRESS DEGRADATION STUDIES USING UV VISIBLE SPECTROSCOPY
| Autor: | Amrita Natekar, Siddhi Naroji |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Chromatography
010405 organic chemistry Hydrochloride Phenylephrine Hydrochloride Pharmacology 010402 general chemistry 01 natural sciences Dosage form 0104 chemical sciences Absorbance chemistry.chemical_compound Ultraviolet visible spectroscopy chemistry Degradation (geology) Caffeine Chlorpheniramine Maleate |
| Zdroj: | International Research Journal of Pharmacy. 7:57-60 |
| ISSN: | 2230-8407 |
| DOI: | 10.7897/2230-8407.07786 |
| Popis: | A simple, precise, accu rate and economic simultaneous UV spectrophotometric method has been developed for the estimation of Paracetamol, Chlorpheniramine Maleate, P henylephrine Hydrochloride and C affeine in tablet formulation. The estimation was based upon the measurement of absorbance at absorbance maxima of 245 nm, 260 nm, 269 nm and 275 nm for Paracetamol, Chlorpheniramine Maleate, P henylephrine Hydrochloride and C affeine in water, respecti vely in tablet dosage form. The method was then validated for di fferent parameters as per ICH (International Conference on Harmonization) guidelines. |
| Databáze: | OpenAIRE |
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