Motor programs interlinking gait and bradykinesia in Parkinson's disease

Autor: Tateo Warabi, Nobuo Yanagisawa, Kiyoharu Inoue
Rok vydání: 2020
Předmět:
Popis: The slowness in Parkinson's disease has been considered to be due to the impairment of movement initiation. Studies of gait in Parkinson's disease investigating EMG off/on latencies from a static posture to the initiation of movement have found unsynchronized off/on latencies in a homogeneous movement, which was correlated statistically with the slow gait speed of bradykinesia. Thus, the slowness was due to the difficulty in terminating the motor program controlling the primary posture. The previous studies concerning impairment of the sequential movements in Parkinson's disease have indicated that bradykinesia is involved in switching the sequence within on/on-latency interval of heterogeneous movements. These recent results elucidate that bradykinesia is involved in the impaired two sensory-motor functions. One is difficulty with the termination of the prior competitive motor program that had been activated in a past time within off/on-latency interval of homogeneous movement. The next is the difficulty in switching to the uncompetitive ongoing motor program sequentially within on/on-latency interval of heterogeneous movements.
Databáze: OpenAIRE