A new strategy for the conversion of aldehydes into difluoromethyl ketones

Autor:	Serge R. Piettre, Charles G. Schelcher, Catherine Girol
Rok vydání:	1996
Předmět:	chemistry.chemical_classification Chemistry Organic Chemistry Drug Discovery Salt (chemistry) chemistry.chemical_element Lithium Biochemistry Medicinal chemistry Bond cleavage Sequence (medicine)
Zdroj:	Tetrahedron Letters. 37:4711-4712
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)00947-1
Popis:	A three-step sequence of reactions involving the lithium salt of diethyl difluoromethylphosphonate as a difluoromethyl carrier is shown to efficiently convert aliphatic and arylic aldehydes 2 into difluoromethyl ketones 1 via an unusual carbon-phosphorus bond scission.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7f68df929ef8232961c78aaafccba91c https://doi.org/10.1016/0040-4039(96)00947-1 Zobrazit plný text záznamu Full Text from ScienceDirect