The asymmetric favorskii rearrangement: A synthesis of optically active α-alkyl amides from aldehydes and (−)-1-chloroalkyl p-tolyl sulfoxide

Autor:	Koji Yamakawa, Tsuyoshi Satoh, Sachiko Kimura, Norio Tokutake, Shigeyasu Motohashi
Rok vydání:	1993
Předmět:	chemistry.chemical_classification Chemistry medicine.drug_class Stereochemistry Organic Chemistry Enantioselective synthesis Carboxamide Sulfoxide Favorskii rearrangement Biochemistry Sulfone chemistry.chemical_compound Drug Discovery medicine Enantiomeric excess Aliphatic compound Alkyl
Zdroj:	Tetrahedron Letters. 34:4823-4826
ISSN:	0040-4039
Popis:	The first asymmetric Favorskii rearrangement is described. Optically active α-alkyl amides of enantiomeric excess up to 94% were realized from aldehydes and optically active (−)-1-chloroalkyl p-tolyl sulfoxides via the Favorskii rearrangement of optically active α-chloro α-sulfonyl ketones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7f3e51230cf75d1c3ee99a22635d05ee https://doi.org/10.1016/s0040-4039(00)74098-6 Zobrazit plný text záznamu