63 EFFECT OF VOLUME OVERLOADED STATES ON THE INDEX OF MYOCARDIAL PERFORMANCE
| Autor: | N. S. Nahman, A. A. Ortiz, S. J. Lavine |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Cardiac function curve
medicine.medical_specialty Ejection fraction business.industry Diastole Left Ventricular Ejection Time Dilated cardiomyopathy General Medicine medicine.disease General Biochemistry Genetics and Molecular Biology medicine.anatomical_structure Ventricle Heart failure Internal medicine medicine Cardiology Myocardial infarction business |
| Zdroj: | Journal of Investigative Medicine. 53:S264.6-S265 |
| ISSN: | 1708-8267 1081-5589 |
| DOI: | 10.2310/6650.2005.00006.62 |
| Popis: | Purpose Index of myocardial performance (IMP) is a systolic-diastolic derived index used to evaluate cardiac function and is a prognostic indicator in patients with myocardial infarction and dilated cardiomyopathy. In an experimental canine model with normal and reduced LV function, volume loading affects (reduces) the IMP by prolonging the left ventricular ejection time (ET). Our objective in this study was to examine IMP in patients with a volume overloaded left ventricle with normal and reduced LV function. Methods The study groups consisted of 157 subjects: 41 normals, 61 with congestive heart failure (CHF) (ejection fraction: 30-50%), and 55 with aortic regurgitation (AR). Of those patients with AR, 13 had CHF. 2D Doppler echocardiography, transmitral, and transaortic spectral Doppler was used to obtain LV size and function. Results When compared to normal subjects (0.37 ± 0.18), IMP was increased in CHF (0.46 ± 0.13, p Conclusions ET is prolonged in AR, a volume overloaded state. Consequently, IMP was insignificantly shortened as compared to normals despite a markedly abnormal DCT suggesting diastolic dysfunction. With CHF, IMP may be falsely low due to a prolonged ET and shortened ICT. IMP should be carefully used as a prognostic indicator. Its application should be cautiously used in states that affect the components of IMP. |
| Databáze: | OpenAIRE |
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