Continuous form-dependent focusing of non-spherical microparticles in a highly diluted suspension with the help of microfluidic spirals
| Autor: | Lisa Sprenger, Tanja Roth, Urs O. Häfeli, Stefan Odenbach |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Fluid Flow and Transfer Processes
Physics Polydimethylsiloxane Mechanical Engineering 010401 analytical chemistry Microfluidics Computational Mechanics 02 engineering and technology 021001 nanoscience & nanotechnology Condensed Matter Physics Secondary flow 01 natural sciences 0104 chemical sciences Suspension (chemistry) Physics::Fluid Dynamics chemistry.chemical_compound chemistry Mechanics of Materials Particle Hydraulic diameter Two-phase flow Composite material 0210 nano-technology Equivalent spherical diameter |
| Zdroj: | Physics of Fluids. 30:045102 |
| ISSN: | 1089-7666 1070-6631 |
| DOI: | 10.1063/1.5019843 |
| Popis: | Microfluidic spirals are able to focus non-spherical microparticles in diluted suspension due to the Dean effect. A secondary flow establishes in a curved channel, consisting of two counter-rotating vortices, which transport particles to an equilibrium position near the inner wall of the channel. The relevant size parameter, which is responsible for successful focusing, is the ratio between the particle diameter of a sphere and the hydraulic diameter, which is a characteristic of the microfluidic spiral. A non-spherical particle has not one but several different size parameters. This study investigated the minor and major axes, the equivalent spherical diameter, and the maximal rotational diameter as an equivalent to the spherical diameter. Using a polydimethylsiloxane (PDMS)-based microfluidic device with spirals, experiments were conducted with artificial peanut-shaped and ellipsoidal particles sized between 3 and 9 μm as well as with the bacteria Bacillus subtilis. Our investigations show that the equi... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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