Problems on autologous blood donation in the case of elderly patients

Autor: Tetsunori Tasaki, Yuriko Tohyama, Mayumi Noguchi, Chokichi Hashimoto, Ryoichi Motoki, Hitoshi Ohto
Rok vydání: 1993
Předmět:
Zdroj: Journal of the Japan Society of Blood Transfusion. 39:923-929
ISSN: 1883-8383
0546-1448
DOI: 10.3925/jjtc1958.39.923
Popis: Analyses were conducted on issues related to autologous blood donation. Out of a total of 840 donor-patients who donated autologous blood prior to elective surgery from November 1987 to March 1993, 138 (16%) presented problems of various kinds. Among them, anemia-related problems are encountered most frequently in adult patients. In regard to donor reactions, 23 cases experienced mild symptoms due to hypovolemia or vasovagal reflex, but recovered by crystalloid infusion.Our data revealed that the etiology of anemia in elderly patients appeared to be a relative iron deficiency: iron sulphate administered was not used efficiently for erythropoiesis but was stored in the reticuloendothelial cells. We also observed an impaired endogenous erythropoietin response to phlebotomy-induced anemia. Therefore, we recommend that recombinant human erythropoietin has the potential for facilitating successful autologous blood donation in selected cases.Incidentally, there seemed to be no use in measurement of the most immature reticulocyte as a parameter to predict successive autologous blood donation in elderly patients.In conclusion, proper attention to such factors as hemoglobin level before donation, age and weight are of importance for successful blood donation; however, we should also put emphasis on patients' general health and complete cooperation.
Databáze: OpenAIRE