The Incidence, Risk, and Consequences of Atrial Arrhythmias in Patients with Continuous-Flow Left Ventricular Assist Devices

Autor:	Meredith A. Brisco, Carmelo A. Milano, Gregory A. Ewald, M.P.H. Lee R. Goldberg M.D., David J. Farrar, David Feldman, Mark S. Slaughter, M.T.R. Jeffrey M. Testani M.D., Kartik S. Sundareswaran
Rok vydání:	2014
Předmět:	Pulmonary and Respiratory Medicine medicine.medical_specialty Ejection fraction Proportional hazards model business.industry Incidence (epidemiology) Hazard ratio medicine.disease Surgery Quality of life Internal medicine Heart failure medicine Cardiology Risk factor Cardiology and Cardiovascular Medicine business Destination therapy
Zdroj:	Journal of Cardiac Surgery. 29:572-580
ISSN:	0886-0440
DOI:	10.1111/jocs.12336
Popis:	Background Although atrial arrhythmias (AAs) are common in heart failure, the incidence of AAs subsequent to the placement of left ventricular assist devices (LVADs) has not been elucidated. Methods Patients receiving a HeartMate II LVAD in the bridge to transplant (n = 490) and destination therapy (n = 634) trials were included (n = 1125). AAs requiring treatment were recorded, regardless of symptoms. Using Cox models with and without a 60-day blanking period, risk factors for early and late AAs were determined. Results In total, there were 271 AAs in 231 patients (21%), most of which occurred within the first 60 days. Patients with and without AAs had similar survival (p = 0.16). Serum creatinine (hazard ratio [HR] = 1.49 per unit increase, 1.18 to 1.88; p
Databáze:	OpenAIRE
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