Two New Stachane Diterpenoids from the Bark of Ptychopetalum olacoides
| Autor: | Yoshiyasu Fukuyama, Qing-Bin Wang, Shu-Jun Zhang, Wan-Xia Tang, Wen-Zhi Zhang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Traditional medicine
010405 organic chemistry Chemistry Plant composition Plant Science General Chemistry 01 natural sciences Nmr data General Biochemistry Genetics and Molecular Biology Terpenoid 0104 chemical sciences 010404 medicinal & biomolecular chemistry Ptychopetalum olacoides Phytochemical visual_art visual_art.visual_art_medium Bioassay Bark |
| Zdroj: | Chemistry of Natural Compounds. 52:841-844 |
| ISSN: | 1573-8388 0009-3130 |
| DOI: | 10.1007/s10600-016-1792-3 |
| Popis: | Phytochemical constituents investigation of the bark of Ptychopetalum olacoides led to the isolation of two new stachane diterpenoides, named stach-15-en-12α-ol-3-one (1) and stach-15-en-12β-ol-3-one (2). The structures of 1 and 2 were elucidated by analyzing spectroscopic data and comparing their NMR data with those of the previously reported compound 1a. The bioassay experiment indicated that compounds 1 and 2 exhibited weak neurite outgrowth-promoting activity on PC12 cells at the concentration of 30 μM. |
| Databáze: | OpenAIRE |
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