The microbiological analysis of the effectiveness of modern antiseptics and antimicrobial materials

Autor: G. G. Nazarchuk, D. P. Oliynyk, I. G. Paliy, O. A. Nazarchuk, O. O. Gonchar, V. G. Paliy
Rok vydání: 2014
Předmět:
Zdroj: Klìnìčna farmacìâ. 18:8-11
ISSN: 2518-1572
1562-725X
DOI: 10.24959/cphj.14.1324
Popis: Effectiveness of antiseptics decasan®(DC), chlorhexidine digluconate (CH), miramistin (MR), antimicrobial composition of decamethoxin (AMC, patent N 74853, Ukraine), antimicrobial dressings against isolated strains of S. aureus (n 32), E. coli (n 25), P. aeruginosa (n 20), C. albicans (n 16) in patients with diabetes having pyo-inflammatory complications has been researched. The antimicrobial properties of antiseptics have been studied by means of the serial dilutions method. The antimicrobial activity of dressings (1.0x1.0 cm), such as medical cotton impregnated with AMC; antiseptic overlay with CH (AOCH); Traumastem Biodress Disinfect®(TBD); activtex CH®, activtex CHF®, against clinical isolates of microorganisms has been studied on solid media. The bactericidal action against S. aureus in the presence of AMC (1.4±0.2 mkg/ml), DC (1.73±0.2 mkg/ml); CH (12.8±2.1 mkg/ml); MR (8.3±0.9 mkg/ml) has been found. The bactericidal properties of DC and MR in relation to E. coli in their concentrations of 6.68±0.71 and 17.9±1.9 mkg/ml, respectively, have been determined. AMC (4.9±0.5 mkg/ml) was six times more active than CH (p
Databáze: OpenAIRE