Research Article Genotypes within the prolactin and growth hormone insulin-like growth factor-I pathways associated with milk production in heat stressed Holstein cattle: Genotypes and milk yield in heat stressed Holstein cows
| Autor: | Hernandez Cordero, M A Sanchez Castro, Zamorano Algandar, Luna Nevarez, G Rincon, J F Medrano, S E Speidel, R M Enns, M G Thomas |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Candidate gene medicine.medical_specialty Coefficient of determination medicine.medical_treatment 0402 animal and dairy science Single-nucleotide polymorphism 04 agricultural and veterinary sciences General Medicine Heritability Biology 040201 dairy & animal science Prolactin 03 medical and health sciences Insulin-like growth factor 030104 developmental biology Endocrinology Animal science Internal medicine Genotype Genetics medicine Molecular Biology Gene |
| Zdroj: | Genetics and Molecular Research. 16 |
| ISSN: | 1676-5680 |
| Popis: | The association of single nucleotide polymorphisms (SNPs) within genes of the prolactin (PRL), growth hormone (GH) and insulin-like growth factor-I (IGF1) pathways with 305-day milk yield (MY305) were evaluated in heat-stressed Holstein cows. Ambient temperature and relative humidity were used to calculate a temperature-humidity index (THI), which revealed that heat stress conditions existed in the Yaqui Valley, Sonora, Mexico from May through October of 2011 and 2012. Cows (n = 573) were genotyped for 179 tag SNPs within 43 candidate genes in the PRL and GH/IGF1 pathways. Seven SNPs within 7 genes (AVPR1A, Furin, IGFBP5, IGFBP6, PMCH, PRLR and STAT5B) were found to be associated with MY305 (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|