Effect of Gallium-68 isotope injection on hemoglobin derivatives concentrations after instant injection and its recovery in male rabbits (Oryctolagus cuniculus)
| Autor: | Bassem M. Raafat, Hamid Osman, Nahla L. Faizo, Sultan Alamri, Ahmad Joman Alghamdi, Rania Mohammed Ahmed, Ashraf Almahwasi |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Applied and Natural Science. 14:677-683 |
| ISSN: | 2231-5209 0974-9411 |
| DOI: | 10.31018/jans.v14i2.3482 |
| Popis: | Oxidizing effects of ionizing radiation are well established and almost understood. However, exposure to low doses of widely used isotopes may result in minor and hidden oxidative stress in some forms of hemoglobin. This formation alteration regarding the legends of hemoglobin's stereochemical function may play a role in hemoglobin dysfunction. There are limited studies related to the effect of gallium isotope injections. The study intends to find the effect of gallium-68 isotope injection on male rabbits. It was conducted on thirty-two male rabbits (Orycytolagus cuniculus) divided into Group I: control and Group II: animals exposed to gallium-68 isotope at a similar dose commonly used in diagnostic protocols for humans. Blood samples were collected twice: the first was after two hours of injection with isotopes and the second was after twelve hours of injection. A linear, four-mathematical-equations matrix based on the Lamber-Beer law was used to measure the concentration of different hemoglobin derivatives. Results revealed a significant elevation (P |
| Databáze: | OpenAIRE |
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