Antifungal Chemistry Review

Autor:	G. Sibley, M. Birch
Rok vydání:	2017
Předmět:	Voriconazole education.field_of_study Tavaborole Population Isavuconazonium Microbiology chemistry.chemical_compound chemistry medicine Anidulafungin Caspofungin education Albaconazole Fluconazole medicine.drug
DOI:	10.1016/b978-0-12-409547-2.12410-2
Popis:	Invasive fungal disease can cause a high degree of mortality within the immunocompromised patient population. Only three classes of antifungal agent are currently in widespread use to treat these infections. Progress has been made with the introduction of third-generation azoles and echinocandins but changes in fungal epidemiology and the emergence of resistant organisms threaten to undermine the effectiveness of these agents. There has been a recent resurgence in antifungal research activity that has led to the discovery of several novel mechanisms based antifungals, active against resistant organisms. These new agents have the potential to improve antifungal therapy and offer treatment for resistant fungal pathogens.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7ed49a0268aa2f63aa26108c2c839339 https://doi.org/10.1016/b978-0-12-409547-2.12410-2 Zobrazit plný text záznamu