T-box RNA gets boxed
| Autor: | Alexander Serganov, Jacob W. Weaver |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
0303 health sciences Messenger RNA Chemistry RNA Amino acid Cell biology 03 medical and health sciences 0302 clinical medicine T-box Structural Biology Transcription (biology) Transfer RNA Gene expression Molecular Biology 030217 neurology & neurosurgery 030304 developmental biology |
| Zdroj: | Nature Structural & Molecular Biology. 26:1081-1083 |
| ISSN: | 1545-9985 1545-9993 |
| DOI: | 10.1038/s41594-019-0340-9 |
| Popis: | Bacterial T-boxes are regulatory mRNA regions that control the transcription or translation of factors involved in amino acid supply. T-boxes act by directly binding to non-aminoacylated tRNA in response to amino acid starvation. Three studies now capture three-dimensional structures of tRNA–T-box complexes and reveal a set of RNA features that are required for the recognition of specific tRNAs and modulation of gene expression. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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