Audit of detection and management of vitamin d deficiency in childhood in the United Kingdom

Autor: PV Dissanayake, R Jayatunge
Rok vydání: 2012
Předmět:
Zdroj: Archives of Disease in Childhood. 97:A119.3-A120
ISSN: 1468-2044
0003-9888
DOI: 10.1136/archdischild-2012-301885.285
Popis: Aims Vitamin D deficiency related to inadequate exposure to sunlight and poor nutritional intake is a growing problem in the United Kingdom. Despite a treatable condition, there are no National guidelines within the NHS providing investigation and treatment protocols for children. We proactively investigate “at risk” (dark pigmented) children for vitamin D deficiency opportunistically and treat according to the Paediatric BNF. Our aim was to ascertain the effectiveness of this strategy. Method Data was collected retrospectively over 12 months on children 0-16 years attending an acute NHS trust that had vitamin D levels tested. Vitamin D deficiency due to other medical problems was excluded. Pre-treatment and follow-up investigations (bone profile, vitamin D and parathormone levels) and treatment given were analysed including the cost implications of both. Results 116 patients were investigated for vitamin D status and 31 (26.7%) had deficiency ( Of the deficient group only 5 (16%) were symptomatic. 61% of the deficient group and only 22% of the insufficient group received recommended treatment. Unfortunately 20% of the deficient and 53% of the insufficient groups were not treated probably due to lack of appreciation of a low result in an asymptomatic child. 25% of the insufficient group was over-treated while 13.3% of the deficient group was under-treated. Recommended follow-up investigations to detect compliance and complications were carried out only in 22% of deficient patients. Conclusion As 84% of vitamin D deficient children were asymptomatic, we conclude that “at risk” children should be proactively investigated. Early treatment of vitamin D insufficiency would prevent the subsequent necessity for more expensive treatment of deficiency. As a significant proportion received inadequate management we highlight the lack of a uniform approach to the management of vitamin D deficiency. A larger multi-centre study is recommended to develop National guidelines defining appropriate investigations and treatment thresholds for vitamin D deficiency and insufficiency in high risk children.
Databáze: OpenAIRE