Scalability and Predictability of Polymorph Transformations Under High Shear
| Autor: | Joshua A. Selekman, Robert Wethman, Steven R. Wisniewski, John M. Wasylyk, Vivek Daftary, Joshua Engstrom, Thomas M. Razler, Tamar Rosenbaum, Federico Lora-Gonzalez, Brendan Mack, Ronald Carrasquillo-Flores, Ming-Hsing Huang, Candi Choi |
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| Rok vydání: | 2021 |
| Předmět: |
Materials science
Basis (linear algebra) 010405 organic chemistry fungi Organic Chemistry food and beverages Thermodynamics 010402 general chemistry 01 natural sciences 0104 chemical sciences law.invention Shear (sheet metal) Transformation (function) law Scalability SCALE-UP Physical and Theoretical Chemistry Solubility Predictability Crystallization |
| Zdroj: | Organic Process Research & Development. 25:1028-1035 |
| ISSN: | 1520-586X 1083-6160 |
| DOI: | 10.1021/acs.oprd.1c00030 |
| Popis: | We show that the behavior of a polymorphic transformation under high shear can be predicted up to pilot scales on the basis of laboratory experiments. Solubility measurements indicate that the tran... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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