Ranitidine in Reflux Oesophagitis

Autor: Geoffrey K.T. Holmes, Varazdad Melikian, Michael R. Lucey, Peter D. Fairclough, Keith R. Hine
Rok vydání: 1984
Předmět:
Zdroj: Digestion. 29:119-123
ISSN: 1421-9867
0012-2823
DOI: 10.1159/000199020
Popis: This study was designed to assess the effect of ranitidine on patients with symptomatic oesophageal reflux. In a double-blind comparative trial in 46 patients a twice daily dose of 150 mg ranitidine was compared with placebo. Relief of pain, endoscopic healing and histological improvement were significantly better in those treated with ranitidine. Thus, ranitidine is of value in the management of patients with reflux oesophagitis and may prevent the development of peptic stricture.
Databáze: OpenAIRE