A magnetic resonance imaging-based classification system for indication of trans-sphenoidal hypophysectomy in canine pituitary-dependent hypercortisolism
| Autor: | Yasushi Hara, Takuya Yogo, Takahiro Teshima, Hirokazu Ishino, Yasuji Harada, Nobuo Kanno, Daisuke Hasegawa, A. Sato |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Hypophysectomy medicine.diagnostic_test Adenoma 040301 veterinary sciences business.industry medicine.medical_treatment Pituitary ACTH hypersecretion Magnetic resonance imaging Retrospective cohort study 04 agricultural and veterinary sciences Pituitary neoplasm medicine.disease Surgery 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Cavernous sinus medicine Clinical significance Small Animals business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Small Animal Practice. 57:240-246 |
| ISSN: | 0022-4510 |
| Popis: | Objectives The objectives of this study were to establish a magnetic resonance imaging-based classification system for canine hyperadrenocorticism according to pituitary gland extension, determine indications for trans-sphenoidal hypophysectomy, and clarify the prognosis for each disease grade. Methods A 5-point classification system (Grades 1 to 5) was developed based on tumour extension in dorsal and cranio–caudal directions. Cases were then classified as Type A: no arterial circle of Willis or cavernous sinus involvement and Type B: cases in which these blood vessels were involved. Results Medical records and magnetic resonance imaging data of 37 cases with hyperadrenocorticism were reviewed. Thirty-three cases underwent surgery; 4 Grade 5 cases did not have appropriate indications for surgery, and other therapies were used. Complete resection was achieved for 3, 3, 22 and 1 Grade 1A, 2A, 3A and 3B cases, respectively. Resection was incomplete in 1, 1 and 2 Grade 3A, 3B and 4B cases, respectively. Remission was achieved in 29 cases. Recurrence occurred in 4 cases, all of which were classified as Grade 3. Clinical Significance Dogs with Type A, Grade 1 to 3 hyperadrenocorticism had a good prognosis following trans-sphenoidal hypophysectomy. Grade 3B, 4 and 5 cases may not be suitable for this surgery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text