Existence of Gαi2-Expressing Axon Terminals in the Goat Main Olfactory Bulb

Autor:	Yuji Mori, Kimiko Hagino-Yamagishi, Masumi Ichikawa, Hiromi Ohara, Hiroaki Okamura
Rok vydání:	2013
Předmět:	General Veterinary Vomeronasal organ Sensory system Biology Accessory Olfactory Bulb Olfactory bulb Cell biology Vomeronasal receptor medicine.anatomical_structure nervous system medicine sense organs Axon Olfactory epithelium
Zdroj:	Journal of Veterinary Medical Science. 75:85-88
ISSN:	1347-7439 0916-7250
DOI:	10.1292/jvms.12-0245
Popis:	In rodents, Gα(i2)-expressing sensory neurons (SNs) that co-express vomeronasal receptor type 1 (V1R) are specifically found in the vomeronasal organ (VNO) and project their axons to the accessory olfactory bulb (AOB). In goats, however, Gα(i2)/V1R-expressing SNs exist in both the VNO and the olfactory epithelium. Thus, we examined whether the Gα(i2)-expressing axons functionally project to the main olfactory bulb (MOB). We analyzed the expression of Gα(i2) in the olfactory bulb and found small Gα(i2)-immunoreactive clusters in the MOB. The Gα(i2)-immunoreactive axons in these clusters made synaptic contacts with second-order neurons in the MOB. These results suggest that some Gα(i2)-expressing SNs functionally project their axons to the MOB in goats.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7e9225ea45358ba17bad893847c7b5a6 https://doi.org/10.1292/jvms.12-0245 Zobrazit plný text záznamu