One pot kinetic resolution and product separation with corn germ oil and supercritical carbon dioxide
| Autor: | Ildikó Kmecz, Zsófia Varga, Edit Székely |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pressure drop
Supercritical carbon dioxide 010405 organic chemistry General Chemical Engineering Separator (oil production) Alcohol 010402 general chemistry Condensed Matter Physics Novozyme 435 01 natural sciences 0104 chemical sciences Kinetic resolution chemistry.chemical_compound chemistry Chemical engineering Germ Physical and Theoretical Chemistry Ambient pressure |
| Zdroj: | The Journal of Supercritical Fluids. 141:218-223 |
| ISSN: | 0896-8446 |
| DOI: | 10.1016/j.supflu.2018.01.014 |
| Popis: | Enantioseparation of 1-phenylethanol with corn germ oil, obtained by supercritical carbon dioxide, is efficiently catalysed by Novozyme 435. The reaction has high enantioselectivity (E > 1000) and the equilibrium conversion is approx. 90% at 50 °C both at ambient pressure and at 20 MPa. The esters and the remaining alcohol can be separated by supercritical carbon dioxide extraction and sequential pressure drop using a pressurized and an atmospheric separator. The determination of suitable pressure and temperature conditions were supported by phase equilibria measurements and distribution ratio determination. |
| Databáze: | OpenAIRE |
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