Expression of Vsx transcription factors in the morphogenesis of retina in the chicken Gallus domesticus

Autor: I. N. Andreichenko, R. D. Zinov’eva
Rok vydání: 2017
Předmět:
Zdroj: Biology Bulletin. 44:113-119
ISSN: 1608-3059
1062-3590
DOI: 10.1134/s1062359017020029
Popis: Using PCR analysis and immunofluorescence staining, we have investigated the expression of homeobox genes Vsx1/Chx10-1 and Vsx2/Chx10 from the Vsx family (visual system homeobox) during retinal morphogenesis in the chicken Gallus domesticus. It was found that the expression of the studied genes starts at the early stages of embryogenesis. It was shown that the proteins of Vsx1 and Vsx2 are localized in the bipolar cells of the inner nuclear layer of the forming retina. The participation of Vsx1/Chx10-1 and Vsx2/Chx1 in the regulation of retinal cell differentiation in various species of vertebrates and in humans was discussed.
Databáze: OpenAIRE