Expression of Vsx transcription factors in the morphogenesis of retina in the chicken Gallus domesticus
Autor: | I. N. Andreichenko, R. D. Zinov’eva |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Genetics Retina Embryogenesis Morphogenesis Homeobox A1 Retinal Biology General Biochemistry Genetics and Molecular Biology Cell biology 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology medicine.anatomical_structure chemistry Inner nuclear layer medicine Homeobox General Agricultural and Biological Sciences Transcription factor |
Zdroj: | Biology Bulletin. 44:113-119 |
ISSN: | 1608-3059 1062-3590 |
DOI: | 10.1134/s1062359017020029 |
Popis: | Using PCR analysis and immunofluorescence staining, we have investigated the expression of homeobox genes Vsx1/Chx10-1 and Vsx2/Chx10 from the Vsx family (visual system homeobox) during retinal morphogenesis in the chicken Gallus domesticus. It was found that the expression of the studied genes starts at the early stages of embryogenesis. It was shown that the proteins of Vsx1 and Vsx2 are localized in the bipolar cells of the inner nuclear layer of the forming retina. The participation of Vsx1/Chx10-1 and Vsx2/Chx1 in the regulation of retinal cell differentiation in various species of vertebrates and in humans was discussed. |
Databáze: | OpenAIRE |
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