Large-scale preparation of .alpha.,.beta.,.alpha.,.beta. atropisomer of meso-Tetrakis(o-aminophenyl)porphyrin

Autor:	Eric Rose, Nathalie Julien, Alain Kossanyi, Louis Hamon, Cecile Pochet, Mélanie Quelquejeu
Rok vydání:	1993
Předmět:	chemistry.chemical_classification Atropisomer Meso compound Stereochemistry Organic Chemistry Nitro compound Medicinal chemistry Porphyrin chemistry.chemical_compound chemistry Yield (chemistry) Nitro Amine gas treating Naphthalene
Zdroj:	The Journal of Organic Chemistry. 58:5030-5031
ISSN:	1520-6904 0022-3263
Popis:	A 72% abundance of α,βα,β-atropoisomer was observed in the thermal treatment of 4 g of meso-5,10,-15,20-tetrakis(o-nitrophenyl)porphyrin in 800 g of naphthalene at 130 o C. The rt reduction of the nitro groups with SnCl 2 and HCl followed by chromatographic separation and precipitation gives the corresponding tetrakis-α,β,α,β-amino atropoisomer in 39% yield
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7e7b4751406d626453f568e949f75c6d https://doi.org/10.1021/jo00071a003 Zobrazit plný text záznamu