A facile route for the synthesis of limonidilactone analogues from andrographolide

Autor: N. R. Srinivas, Sanjeeva Rao Thunuguntla Siva, Kumar Nyavanandi Vijay
Rok vydání: 2004
Předmět:
Zdroj: Tetrahedron Letters. 45:9357-9360
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2004.10.135
Popis: Labdane diterpenes are an important class of natural products with a wide variety of biological properties. (−)-Limonidilactone is a labdane diterpene with a novel skeleton isolated from Vitex limonifolia. A new semi-synthetic route from andrographolide, the major constituent of Andrographis paniculata, has been described towards the synthesis of novel labdanes having a limonidilactone type skeleton.
Databáze: OpenAIRE