Clinical Trial Protocol for LuTectomy: A Single-arm Study of the Dosimetry, Safety, and Potential Benefit of 177Lu-PSMA-617 Prior to Prostatectomy
| Autor: | Shahneen Sandhu, Simon P. Keam, Scott Williams, Catherine Mitchell, Michael S Hofman, Paul J Neeson, Renu Eapen, Nathan Lawrentschuk, Price Jackson, Omar Alghazo, Arun Azad, Declan G. Murphy, Mark Scalzo, Nattakorn Dhiantravan, Daniel Moon, John Violet |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
177Lu-PSMA-617 business.industry Prostatectomy Urology medicine.medical_treatment 030232 urology & nephrology medicine.disease Clinical trial 03 medical and health sciences Dissection Prostate cancer 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Medicine Dosimetry business Lymph node Single Arm Study |
| Zdroj: | European Urology Focus. 7:234-237 |
| ISSN: | 2405-4569 |
| DOI: | 10.1016/j.euf.2020.09.021 |
| Popis: | LuTectomy is an open-label phase 1/2 nonrandomised clinical trial evaluating the dosimetry, efficacy, and toxicity of the lutetium-177-radiolabelled small molecule PSMA-617 in men with high-risk localised/locoregional advanced prostate cancer with high prostate-specific membrane antigen expression who are undergoing radical prostatectomy and pelvic lymph node dissection. |
| Databáze: | OpenAIRE |
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