| Autor: |
Thierry Bilbault, David J. Keith, Bor-Shyue Hong, Masood A. Chowhan, F. Darell Turner, Ronald P. Quintana, Barry F. Van Duzee |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
International Contact Lens Clinic. 21:237-242 |
| ISSN: |
0892-8967 |
| DOI: |
10.1016/0892-8967(94)90057-4 |
| Popis: |
The cleaning capability of citrate and the comparative capability of Opti-One™ Multi-Purpose Solution and ReNu® Multi-Purpose Solution were assessed by the removal of lysozyme deposits from Group IV hydrogel contact lenses. The in vitro model used DuraSoft® 3 lenses deposited with fluorescently labeled dansyl-lysozyme. Quantitative determination of the dansyl-lysozyme removed was accomplished by fluorescence spectrophotometry. The results demonstrated that solutions containing citrate, Opti-One Multi-Purpose Solution, and Test Solution A (Opti-One without Polyquad®), removed significantly (p < 0.05) more dansyl-lysozyme than did test solutions without citrate and ReNu Multi-Purpose Solution (a surfactant-based cleaner). This was accomplished by soaking in the test solutions (passive cleaning) and did not involve a digital rub of the lenses. The citrate's mode of action is thought to involve complexation with and displacement of lens-associated lysozyme into the aqueous cleaning solution medium. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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