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Introduction: The treatment for Ductal Carcinoma in situ (DCIS) can be mastectomy, breast-conserving surgery with or without adjuvant Radiotherapy (RT). Regarding the conserving treatment, ipsilateral recurrence is the main reason of concern. Randomized studies show that RT reduces the risk of local recurrence (LR). Age, comedonecrosis, absence of endocrine therapy (ET) and positive margins are also prognostic factors. Objective: To assess the local relapse-free survival (LRFS) of patients with DCIS treated with breast-conserving surgery, followed by adjuvant RT, and to identify possible prognostic factors related to LR. Method: between March 2007 and December 2017, we identified 95 women diagnosed with DCIS and treated with breast-conserving surgery and adjuvant RT in Hospital São Paulo (HSP/UNIFESP). Regarding RT, we used the 3D technique with conventional fractionation (50/50.4 Gy and 2/1.8 Gy fraction per day), or hypofractionation (40 Gy and 2.67 Gy fraction per day). The data were submitted to descriptive analysis and evaluation of LR. Factors such as characteristics of the patients, the tumor and the treatment were correlated by using Fisher’s Exact Test and Kruskall-Wallis test. The log-rank test was used for the Kaplan-Meier comparison. The results were considered as statistically significant when p |
