Smectite clay KSF as effective catalyst for oxidation of m-tyrosol with H2O2 to hydroxytyrosol

Autor: Mohamed Bouaziz, Geoffrey Kit, Soumaya Bouguerra, Ridha Abdelhedi, Nourzed Frikha
Rok vydání: 2019
Předmět:
Zdroj: Reaction Kinetics, Mechanisms and Catalysis. 127:505-521
ISSN: 1878-5204
1878-5190
Popis: A successful procedure to demonstrate the ability to produce high-added value phenolic hydroxytyrosol by oxidation of m-tyrosol was developed, using clay KSF/H2O with peroxide hydrogen to afford excellent yields (more than 60%). Three different operating parameters, including m-tyrosol, H2O2 concentration and amount of catalyst were performed using an experimental design methodology “Box–Behnken” for hydroxytyrosol production. All derivative compounds in reaction mixture during reaction time were identified using mass spectrometry. Hydroxytyrosol 3,4-dihydroxystyrene; 3-hydroxyphenyl acetic acid and 2.5-dihydroxyphenylethanol were the major compounds. By means of 2,2-diphenyl-1-picrylhydrazyl DPPH method, the antioxidant activity was realized, indicating that the strongest antiradical activity (IC50% = 21.57 mg/mL) was detected when the concentration of hydroxytyrosol is higher. The developed synthesis, investigated for the first time, is operationally simple and could find application for industrial purposes.
Databáze: OpenAIRE
Externí odkaz: