A study of grouped failure time data and the misapplication of recurrent event modeling

Autor: Neil Klar, Melissa C. Braschel, Gerarda Darlington
Rok vydání: 2017
Předmět:
Zdroj: Communications in Statistics - Simulation and Computation. 46:5313-5322
ISSN: 1532-4141
0361-0918
DOI: 10.1080/03610918.2016.1152367
Popis: Clinical trials often assess whether or not subjects have a disease at predetermined follow-up times. When the response of interest is a recurrent event, a subject may respond at multiple follow-up times over the course of the study. Alternatively, when the response of interest is an irreversible event, a subject is typically only observed until the time at which the response is first detected. However, some recent studies have recorded subjects responses at follow-up times after an irreversible event is initially observed. This study compares how existing models perform when failure time data are treated as recurrent events.
Databáze: OpenAIRE