Living in Rural Areas of Peninsular Malaysia: Risk Factor for Goitre

Autor:	Shahar MA, Omar AM, AB Wahab N, Sukor N, Kamaruddin NA
Rok vydání:	2020
Předmět:	medicine.diagnostic_test business.industry Thyroid Ethnic group General Medicine Palpation Anti-thyroid autoantibodies medicine.anatomical_structure Medicine Medical history Rural area Risk factor business Disease burden Demography
Zdroj:	IIUM Medical Journal Malaysia. 18
ISSN:	2735-2285 1823-4631
DOI:	10.31436/imjm.v18i3.196
Popis:	Introduction: Thyroid disorders are among common medical conditions encountered in clinical practice. However, the disease burden among Malaysian population has not been established. This study was aimed to determine the prevalence of goitre and its associated factors among adult population in Peninsular Malaysia. Materials and Methods: A cross-sectional study was performed in 5 pre-assigned regions in Peninsular Malaysia. Participants’ sociodemographic profile and medical history were recorded. Physical examinations were done looking for abnormalities of the thyroid gland and signs of thyroid dysfunctions. The diagnosis of goitre was made by palpation and corroborated by the repeat examination by another investigator. The World Health Organization (WHO) goitre grading system was used. Fifteen millilitre of blood were withdrawn and analysed at a central laboratory. Results: Among 2190 respondents, the prevalence of goitre was 9.3%. Goitre was associated with positive anti-thyroperoxidase and anti-thyroglobulin antibodies. Females were at higher risk of goitre (adjusted OR = 2.4; 95% CI 1.6–3.5; p
Databáze:	OpenAIRE
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