A synthetic encapsulating emulsifier using complex-forming pentacosadiynoyl cyclosophoraoses (cyclic β-(1, 2)- d -glucan)
| Autor: | Seunho Jung, Eunae Cho, Bong-Hyun Jun, Seyeon Park, Daham Jeong, Hwanhee Kim, Someshwar D. Dindulkar |
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| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry General Chemical Engineering Bioactive molecules 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences Combinatorial chemistry 0104 chemical sciences Sudan III chemistry.chemical_compound chemistry Lipophilicity Moiety Molecule Organic chemistry 0210 nano-technology Two-dimensional nuclear magnetic resonance spectroscopy Glucan |
| Zdroj: | Journal of Industrial and Engineering Chemistry. 44:195-203 |
| ISSN: | 1226-086X |
| Popis: | A new pentacosadiynoyl cyclosophoraose (P-Cys) was synthesized using a biosourced cyclooligosaccharide with intrinsic complexation capacity. NOESY analysis revealed that switchable molecular behavior of pentacosadiynoyl moiety attached to P-Cys was dependent on the external lipophilicity. Both encapsulation by cyclosophoraose and switchable emulsification by pentacosadiynoyl moiety in P-Cys make it possible to finely formulate a nanoemulsion state for an external hydrophobic guest molecule like Sudan III. Various physicochemical properties of the emulsions of P-Cys were investigated using TEM and DLS. The results indicate that P-Cys is a useful potential platform for the encapsulating emulsification of bioactive molecules for cosmetic and pharmaceutical applications. |
| Databáze: | OpenAIRE |
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