Deep Infections in Total Joint Replacements

Autor:	Suhel Kotwal
Rok vydání:	2013
Předmět:	medicine.medical_specialty Osteolysis business.industry Bone stock Genitourinary system Total Joint Replacements Perioperative Hematogenous Spread medicine.disease Surgery Medicine Orthopedics and Sports Medicine Implant business Prosthetic infection
Zdroj:	Orthopedics. 36:362-363
ISSN:	1938-2367 0147-7447
DOI:	10.3928/01477447-20130426-05
Popis:	Define what constitutes a deep prosthetic infection. Contamination, concentration, and multiplication of microorganisms in a joint surgically treated with prosthetic reconstruction constitute deep prosthetic infection. The most frequent microorganisms found are bacteria, but fungal infections are often seen, especially in individuals who are immunocompromised. Acute infections result from the perioperative contamination of the surgical field, and chronic infections are frequently the result of hematogenous spread from a distant focus, including but not limited to, dental, respiratory, gastrointestinal, or genitourinary origin. Toxins released by the microorganisms combine with the body’s inflammatory response, resulting in steady destruction of juxta-articular bone stock, osteolysis, and implant loosening with dramatic medical and socioeconomic sequelae.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7dd2a1cf30ecf773fda30ff55e8aee91 https://doi.org/10.3928/01477447-20130426-05 Zobrazit plný text záznamu