Effects of Geophagy on Hemoglobin Level and Iodine Absorption /Assimilation in Albino Rats
| Autor: | Chelea M, Lantum Dn, Mbofung Cmf, Bonglaisin Jn, Djiele Pn, Tsafack Tjj, Ngondé Emc |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
business.industry Thyroid chemistry.chemical_element Assimilation (biology) Hemoglobin levels Calcium Iodine Bioavailability Excretion Endocrinology medicine.anatomical_structure Animal science chemistry hemic and lymphatic diseases Internal medicine Medicine Hemoglobin business |
| Zdroj: | Journal of Nutritional Disorders & Therapy. |
| ISSN: | 2161-0509 |
| DOI: | 10.4172/2161-0509.1000211 |
| Popis: | Geophagic behaviour has been reported to increase exposure to Lead (Pb) that could influence the bioavailability and assimilation of iron and iodine through metal-metal interactions. Similarly, calcium that is naturally contained in kaolin tends to inhibit the absorption and assimilation of iron. In order to investigate these interactions 80 female albino rats aged 12 weeks and weighing between 212-261g were served with Pb contaminated kaolin pellets in a manner to simulate human consumption of this clay. The size, content of the thyroid gland in iodine, urinary/faecal iodine excretion and hemoglobin level were analytically monitored during this experiment and statgraphic 5.0 used for data analyses. The results show increased thyroid volume, decreased thyroid iodine content, increased urinary iodine excretion and adequate iodine absorption as kaolin is introduced into an iodine sufficient diet. Hemoglobin levels of the various test groups compared to the control group are statistically significant. The study reveals that that kaolin-eating does not influence iodine absorption but, it influences its assimilation at the level of the thyroid gland in albino rats. The study also reveals that the consumption of kaolin affects hemoglobin level. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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