B12 Vitamini Eksikliğinde Görsel Uyandırılmış Potansiyeller: Ön Çalışma Sonuçları
| Autor: | Yildiz Degirmenci, Ceyda Hayretdag Ors, Yeliz Yilmaz, Handan Işın Özışık Karaman |
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| Rok vydání: | 2012 |
| Předmět: |
Vitamin
medicine.medical_specialty genetic structures medicine.diagnostic_test business.industry Complete blood count Visual evoked potentials medicine.disease Gastroenterology Thyroid function tests chemistry.chemical_compound Endocrinology chemistry P100 Latency Internal medicine medicine Optic nerve Optic neuritis Vitamin B12 business |
| Zdroj: | Journal of Inonu University Medical Faculty. 19:96-99 |
| ISSN: | 1300-1744 |
| DOI: | 10.7247/jiumf.19.2.6 |
| Popis: | Objective: Aim of this study was to investigate the possible relationship between serum vitamin B12 levels and P100 latency and amplitudes with visual evoked potentials (VEP) in patients with B12 vitamin deficiency without optic neuritis (ON). Material and Methods: Patients who presented to the outpatient neurology clinic of Canakkale Onsekiz Mart University Research Hospital underwent initial evaluation. Among those, complete blood count, full biochemistry (blood glucose, liver and kidney function tests, electrolites) and thyroid function tests were performed to the patients with serum B12 vitamin levels l200 pg/dl and without optic neuritis who accepted to participate. Electrophysiological evaluations included VEP. Data were organized in SPSS 15.0 programme and statistical analysis were performed in this programme. Non-parametric correlation test and Spierman's rho tests were used for statistical analysis. Results: Patients enrolled the study consisted of 13 (68.4%) men and 6 (31.6%) women. Mean age was 52.68p15.10 years (range=19-75 years). Mean vitamin B12 levels were160.41p44.59 pg/ml (range=78-230 pg/ml). There was no statistically significant correlation between serum vitamin B12 levels and P100 latency and amplitudes (pg0.05). Conclusion: Our results reveals that there is no correlation between the VEP values and the severity of vitamin B12 deficiency in the absence of ON in patients with vitamin B12 deficiency. Study still continues, but results of the preliminary study are shared in order to discuss the value of VEP in patients with vitamin B12 deficiency without ON. Key words: Vitamin B12 Deficiency; Optic Nerve; Visual Evoked Potentials. |
| Databáze: | OpenAIRE |
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