AMELIORATIVE ANTIUROLITHIATIC EFFECT OF A POLYHERBAL SUSPENSION

Autor: Ameeta Argal, Nishi Saxena
Rok vydání: 2014
Předmět:
Zdroj: Journal of Drug Delivery and Therapeutics. 4
ISSN: 2250-1177
Popis: A polyherbal suspension was prepared for use in urolithiasis. Three drugs namely Cyperus rotundus roots, Azadirachta indica leaves and Bryophyllum pinnatum leaves were used in the formulation. Antiurolithiatic activity was studied in the ethylene glycol induced urolithiasis model at a dose of 100, 200 and 300mg/kg polyherbal suspension in wistar rats. Cystone was used as the standard drug. All the doses were found to be effective in a dose related manner. There was an increase in the urinary excretion of calcium, oxalate, phosphate, urea, uric acid and creatinine significantly in the suspension treated group. P
Databáze: OpenAIRE