Oligomeric guanidine synthesis assisted by TFA-sensitive arylsulfonylthiourea

Autor:	Zhongsheng Zhang, Erkang Fan, Tyan L. Carter
Rok vydání:	2003
Předmět:	chemistry.chemical_compound Thiourea Chemistry Organic Chemistry Drug Discovery Organic chemistry Guanidine Biochemistry
Zdroj:	Tetrahedron Letters. 44:3063-3066
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(03)00543-4
Popis:	Through arylsulfonyl activation of thiourea, efficient synthesis of oligomeric guanidines can be achieved in either solution or solid-phase. Incorporation of TFA-sensitive arylsulfonyl groups, such as Pbf, during the synthesis greatly simplifies deprotection procedures for obtaining the final oligomeric guanidine products.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7d912361f5d06266b0f32d26979ac6dd https://doi.org/10.1016/s0040-4039(03)00543-4 Zobrazit plný text záznamu Full Text from ScienceDirect