Autor: Peter Brinsden, A. Gerrard, Fidelis Akagbosu, Amir Lass, N. Abusheikha
Rok vydání: 2000
Předmět:
Zdroj: Journal of Assisted Reproduction and Genetics. 17:566-573
ISSN: 1058-0468
DOI: 10.1023/a:1026485830540
Popis: Objectives: The aim was to evaluate whether women who have early follicular follicle-stimulating hormone (FSH) levels >12 mIU/ml have reduced response to follicular stimulation for in vitro fertilization (IVF) in a following month, in spite of normal FSH levels. Materials and methods: In a 3-year period from January 1996 to December 1998, 303 women aged 38 years and above and/or who had previously responded poorly to superovulation for IVF gave blood samples for FSH, luteinizing hormone (LH), and estradiol (E2) on day 2 of menstruation before commencing treatment. Results: In 117 (38.6%) of these women, FSH levels were >12 mIU/ml (range 12–114 mIU/ml). Sixty-six of these women gave a further 130 blood samples for FSH measurement in the following months. Seventy-eight (60.0%) of the tests showed raised FSH value >12 mIU/ml. Thirty women whose repeat FSH levels were 12 mIU/ml had an increased risk (>50%) that in subsequent cycles levels would remain raised, and it was not possible to predict which individuals would have favorable FSH levels. If the cycle day 2 FSH level returns to a “normal” level of
Databáze: OpenAIRE
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