Antibacterial Activity of Spruce Bark (Picea abies L.) Extract against Escherichia coli
| Autor: | Silvia Oroian, Felicia Toma, Sanda Cosarca, Corneliu Tanase, Irina Boz, Anca Mare, Adrian Man |
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| Rok vydání: | 2018 |
| Předmět: |
fungi
Picea abies General Medicine Biology 010402 general chemistry medicine.disease_cause biology.organism_classification 01 natural sciences 0104 chemical sciences 03 medical and health sciences 0302 clinical medicine Plant science visual_art Botany medicine visual_art.visual_art_medium Bark Antibacterial activity Escherichia coli 030217 neurology & neurosurgery |
| Zdroj: | Acta Biologica Marisiensis. 1:5-9 |
| ISSN: | 2668-5124 |
| DOI: | 10.2478/abmj-2018-0001 |
| Popis: | The increase of antibiotic resistant bacteria in lasts years resulted in limited options for treatment of bacterial diseases. Escherichia coli is one of the most common Gram-negative bacterial pathogen and a cause of both community and hospital acquired infections. Medicinal plants are alternative rich sources of useful antibacterial agents. The antimicrobial activities of the spruce (Picea abies L.) bark polyphenolic extracts were examined for their capacity to inhibit the growth of Escherichia coli. Spruce bark extract was obtained by conventional aqueous extraction and with ultrasounds. The minimum inhibitory concentration was determined by microdilution method. The antibacterial effect of both extracts was strong against Escherichia coli. The antimicrobial effect of polyphenolic extracts on Escherichia coli was expressed at a concentration of 15 mg/ml. Antimicrobial activity of spruce bark compounds suggest a possible use of spruce bark in pharmaceutical preparations. |
| Databáze: | OpenAIRE |
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