Synthesis of Seleno Oxindoles via Iodine-Induced Radical Cyclization of N-Arylacrylamides with Diorganyl Diselenides
| Autor: | Qing-Wen Gui, Juan Du, Hongmei Jiang, Haicheng Shen, Cehua Li, Zheng Jin, Yanxue Shang, Yufeng Chen, Min Yi |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Synthesis. 54:2669-2676 |
| ISSN: | 1437-210X 0039-7881 |
| Popis: | A mild, radical cascade cyclization of N-arylacrylamides with diselenides for the preparation of oxindoles via iodine oxidation is disclosed that provides an environmentally friendly process for the construction of C–Se bonds. Twenty-five examples of N-arylacrylamide substrates were investigated, and excellent yields were achieved. The tandem cyclization of acrylamide with diphenyl disulfide was also applicable under the same conditions. |
| Databáze: | OpenAIRE |
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