Autopsy, radiographic, and prenatal ultrasonographic examination of a stillborn fetus with femoral facial syndrome

Autor:	Michael W. Stannard, Ronald M. Ramus, Beverly Barton Rogers, Jill E. Urban
Rok vydání:	1997
Předmět:	Fetus Pregnancy business.industry Long bone Autopsy Anatomy medicine.disease Hypoplasia Gestational diabetes medicine.anatomical_structure medicine Gestation Femur business health care economics and organizations Genetics (clinical)
Zdroj:	American Journal of Medical Genetics. 71:76-79
ISSN:	1096-8628 0148-7299
DOI:	10.1002/(sici)1096-8628(19970711)71:1<76::aid-ajmg14>3.0.co;2-s
Popis:	Femoral facial syndrome (FFS) is comprised of cleft palate, micrognathia, short or absent femora, and vertebral and genitourinary malformations. We report on a stillborn fetus with FFS delivered to a mother with gestational diabetes. Prenatal ultrasound examination showed abnormalities at 21 weeks of gestation; prior ultrasound findings were interpreted as normal. Long bone histology showed disorganization of the growth plate with a relative decrease in cartilaginous matrix and vacuolization and binucleation of the chondrocytes.
Databáze:	OpenAIRE
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