Neonatal lymphatic flow disorders: impact of lymphatic imaging and interventions on outcomes
| Autor: | Mandi Liu, Erin Pinto, Chitra Ravishankar, Catherine Williams, Jonathan J. Rome, Yoav Dori, Aaron G. DeWitt, Andrew C. Glatz, Dalal Taha, Christopher L. Smith, Huayan Zhang, Ganesh Krishnamurthy, Fernando Escobar, David M. Biko, Heather Griffis |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Obstetrics and Gynecology Chylothorax Retrospective cohort study medicine.disease Anasarca Thoracic duct Surgery 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Lymphatic system 030225 pediatrics Pediatrics Perinatology and Child Health Ascites Medicine 030212 general & internal medicine Embolization medicine.symptom business Neonatal Disorder |
| Zdroj: | Journal of Perinatology. 41:494-501 |
| ISSN: | 1476-5543 0743-8346 |
| DOI: | 10.1038/s41372-020-00771-3 |
| Popis: | Neonatal chylothorax (NCTx) and central lymphatic flow disorder (CLFD) are historically challenging neonatal disorders with high morbidity and mortality. METHODS We conducted a retrospective study of 35 neonates with pulmonary lymphatic abnormalities at our institution who underwent lymphatic evaluation between December 2015 and September 2018. Patients with only pulmonary lymphatic perfusion syndrome were classified as NCTx and those with multiple flow abnormalities were classified as CLFD. Demographics, clinical characteristics, and outcomes were compared using t-tests/Wilcoxon rank sum tests and Fisher's exact tests. RESULTS All 35 patients had intranodal MR lymphangiography and 14 (40%) also had conventional fluoroscopic lymphangiography. Fifteen (42.8%) patients were diagnosed with NCTx and 20 (57.1%) were diagnosed with CLFD. Thirty-four (97.1%) patients had pleural effusions. None of the NCTx group had ascites, anasarca, or dermal backflow compared to 17 (85%) (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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