Chronic Inflammatory Demyelinating Polyneuropathy: Immunoglobulins or Plasmapheresis?

Autor: Wim I. M. Verhagen, Mathé J. J. Prick
Rok vydání: 1991
Předmět:
Zdroj: Archives of Neurology. 48:1118-1119
ISSN: 0003-9942
DOI: 10.1001/archneur.1991.00530230026013
Popis: To the Editor. —Chronic inflammatory demyelinating polyneuropathy is a disease of the peripheral neuron with unknown cause. Management of the disorder is still a subject of study. Recently, several studies 1-5 have demonstrated that treatment with high-dose intravenous immunoglobulin has a clear effect on chronic inflammatory demyelinating polyneuropathy. Repeated treatments for a long period are common. 5 In some cases, it might be better to use plasma exchange. 6 We present a patient with chronic inflammatory demyelinating polyneuropathy who was treated with high-dose intravenous immunoglobulin several times, resulting in short-term amelioration with rapid new deterioration with an initially unknown cause; plasma exchange caused rapid improvement without new deterioration. Report of a Case. —A 66-year-old man was admitted with paresthesia of the lower limbs that had appeared rather suddenly. Later on, progressive weakness of the legs developed, which gradually extended to the arms over a period of several weeks. There were
Databáze: OpenAIRE