| Autor: |
Kumar Venkitanarayanan, Deepti Prasad Karumathil, Indu Upadhyaya, Varunkumar Bhattaram, Abhinav Upadhyay |
| Rok vydání: |
2016 |
| Předmět: |
|
| DOI: |
10.1016/b978-0-12-803642-6.00010-1 |
| Popis: |
The emergence of multidrug resistance (MDR) in pathogenic bacteria and escalating concerns over the slow rate of development of novel antibiotics have led to a renewed interest in exploring the potential of alternate strategies to combat infections caused by antibiotic-resistant bacteria. Plant-derived compounds are secondary metabolites that are being extensively studied to develop novel antimicrobials against MDR microbes. Traditionally, plant extracts have been used in herbal and complementary medicine for the treatment of various diseases. A plethora of plant compounds with a wide spectrum of activity against bacterial pathogens have been identified, and several active components have been characterized. However, research investigating their efficacy in reversing antimicrobial resistance development or reducing spread of resistance determinants is scanty. This chapter highlights the potential of plant-derived compounds for controlling antibiotic-resistant bacteria. Furthermore, studies highlighting the diverse effects exerted by plant compounds on various factors that facilitate the development and spread of resistance determinants are discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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