STUDIES ON FOLIC ACID IN INFANCY
| Autor: | Nathan Grossowicz, Shulamith Bar-Shani, Rina Zamir, Yehuda Matoth |
|---|---|
| Rok vydání: | 1964 |
| Předmět: |
medicine.medical_specialty
Pregnancy medicine.diagnostic_test business.industry food and beverages medicine.disease Gastroenterology Infant nutrition disorder Bone marrow examination Folinic acid Malnutrition Diarrhea medicine.anatomical_structure Internal medicine Pediatrics Perinatology and Child Health Immunology medicine Bone marrow medicine.symptom business Whole blood medicine.drug |
| Zdroj: | Pediatrics. 33:694-699 |
| ISSN: | 1098-4275 0031-4005 |
| DOI: | 10.1542/peds.33.5.694 |
| Popis: | Folic acid was assayed microbiologically in whole blood in a group of infants hospitalized for diarrhea, various infections, and malnutrition. Folic acid activity was decreased in the majority of cases. In some of the infants very low levels were observed. The value of the determination of folic acid in whole blood as a sensitive index of the folic acid status of an individual was confirmed by parallel observations on bone marrow morphology and the level of folic acid in serum. Folinic acid levels were within the normal range in most cases. Low folinic acid levels were common only when folic acid was extremely low. Many patients with low folic acid levels were not anemic, or mildly anemic. In the anemic patients a hypochromic microcytic blood picture was the rule. The effect of treatment with folic acid on the general condition of the patients was more striking than the hematological response. |
| Databáze: | OpenAIRE |
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