Non-specific Ventilatory Defect Predicts Nocturnal Hypoxemia in Subjects with Obesity

Autor: Ishan Lalani, Shoji Shimizu, Faisal Qadir, Mirna Ayache
Rok vydání: 2023
DOI: 10.21203/rs.3.rs-2980769/v1
Popis: Although nocturnal hypoxemia has been linked to obesity, the relationship between spirometry parameters and nocturnal oxygen saturation (SpO2) has not been well studied in subjects with obesity. This a retrospective cross-sectional chart review of adult patients with obesity, who had PFT (pulmonary function tests) and diagnostic polysomnogram within 6 months between 2017-2019. A total of 227 patients were included in the analysis, of which 69% were females and 43.8% were African Americans. In the absence of obstruction on spirometry, FEV1 (forced expiratory volume in first second) and FVC (forced vital capacity) were associated with lower mean nocturnal SpO2. Non-specific ventilatory defect on PFTs was associated with increased odds of having a mean nocturnal SpO2
Databáze: OpenAIRE