Novel, high-amplitude blood-flow oscillations in vasodilating human skin
| Autor: | Cassandra D. Haley, Arthur B. Jenkins, Nigel A.S. Taylor, Annerieke Zeyl |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
High amplitude Physiology Skin blood flow Chemistry Vasomotion Human skin Vasodilation Propranolol Laser Doppler velocimetry Biochemistry Endocrinology Internal medicine medicine Biophysics General Agricultural and Biological Sciences Perfusion Developmental Biology medicine.drug |
| Zdroj: | Journal of Thermal Biology. 29:717-723 |
| ISSN: | 0306-4565 |
| Popis: | While investigating cutaneous perfusion during rewarming from cold-water immersion (18 °C), we observed high-amplitude oscillations in skin blood flow. This novel phenomenon occurred during whole-body heating (40 °C) with, and without, β -adrenergic blockade, but was not present during basal thermoneutral conditions (28 °C). Blood-flow oscillations (∼0.4 Hz), spanning ∼700–800 ms were observed during both rewarming phases, and were comprised of high-amplitude peaks (∼1500 AU) arising from a stable baseline (∼200 AU). Propranolol treatment had no effect on these oscillations. A second experiment was conducted to determine whether pre-cooling was essential to the induction of such oscillations. Herein we provide the first description of these novel oscillations. We hypothesise that these oscillations were influenced by variations in core and skin temperatures, and we are currently exploring the control mechanisms and the physiological significance of these high-amplitude oscillations. |
| Databáze: | OpenAIRE |
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